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Effect of the rs374810 <t>of</t> <t>RSPO2</t> on the promotor activity. The promoter activity of the promotor <t>SNP</t> rs374810 of RSPO2 according to the alleles was measured using luciferase reporter system. The promotor activity of the minor allele of rs374810 (the A allele) was shown to be increased, compared to the major allele (the G allele).
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Effect of the rs374810 of RSPO2 on the promotor activity. The promoter activity of the promotor SNP rs374810 of RSPO2 according to the alleles was measured using luciferase reporter system. The promotor activity of the minor allele of rs374810 (the A allele) was shown to be increased, compared to the major allele (the G allele).

Journal: Psychiatry Investigation

Article Title: Association Between Gene Polymorphisms of RSPO2 of the Wnt Signaling Pathway and Schizophrenia in the Korean Population

doi: 10.30773/pi.2025.0020

Figure Lengend Snippet: Effect of the rs374810 of RSPO2 on the promotor activity. The promoter activity of the promotor SNP rs374810 of RSPO2 according to the alleles was measured using luciferase reporter system. The promotor activity of the minor allele of rs374810 (the A allele) was shown to be increased, compared to the major allele (the G allele).

Article Snippet: SNPs of RSPO2 were selected from the National Center for Biotechnology Information SNP database ( https://www.ncbi.nlm.nih.gov/gene/340419 ).

Techniques: Activity Assay, Luciferase